A closer look at the discovery
The skin barrier is our body’s first line of defence, protecting us from dehydration, infections, and harmful substances. In this study, researchers identified the role of hFWE4 in transporting essential building blocks to the outer layer of the skin. This transport process is crucial for forming a healthy, functioning barrier.
By revealing this mechanism, the study provides new insights into why certain genetic conditions disrupt the skin’s protective function and offers potential pathways for developing treatments in the future.
Our contribution
At Locsense, we’re proud to have played a role in making this research possible. Using our automated TEER and impedance spectroscopy measurement solutions, the research team could monitor processes in living cells with extreme precision without causing damage.
Our technology helped visualise processes that are normally invisible, enabling the researchers to track cellular activity in unprecedented detail. This capability was key to uncovering the role of hFWE4 in skin barrier formation.
Pushing the boundaries of bioscience
This breakthrough, now formally recognised through its publication in Nature Communications, demonstrates how advanced sensing technologies like ours can drive progress in biomedical research. It’s another example of how our innovations can help scientists answer fundamental biological questions and bring us closer to real-world healthcare solutions.
