
Beyond the barriers: impedance-based quality control of in vitro lung models
Chronic pulmonary diseases are a high burden on the healthcare system and on the quality of life (QoL)of its patients....
Read moreChronic pulmonary diseases are a high burden on the healthcare system and on the quality of life (QoL)of its patients....
Read moreThe blood-brain barrier (BBB) is a highly specialized and complex physiological structure that plays acrucial role in maintaining the homeostasis...
Read moreFor research into skin biology, diseases, and drug or chemical interactions, organotypic 3D human epidermal equivalents (HEEs) are frequently used....
Read moreThe human rena is a highly organized structure consisng of neural rena, renal pigment epithelial (RPE)cell layer, and vasculature, called...
Read moreFor research into skin biology, diseases and drug or chemical interactions, organotypic 3D human epidermal equivalents (HEEs) are frequently used....
Read moreCOPD is a major global cause of mortality, but current treatmentsonly provide symptomatic relief. Limited progress in developing new therapies...
Read moreEver since the association between FLG loss-of-function variants and ichthyosis vulgaris and atopic dermatitis disease onset was identified, FLGs function...
Read moreBackground Respiratory diseases are the 2nd leading cause of death globally. The current treatments for chronic lung diseases are only...
Read moreThe aryl hydrocarbon receptor (AHR) is an evolutionary conserved environmental sensor identified as indispensable regulator of epithelial homeostasis and barrier...
Read more3 D human epidermal equivalents (HEEs) are a state‐of‐the‐art organotypic culture model in preclinical investigative dermatology and regulatory toxicology. Here,...
Read moreNearly 2500 years ago Hippocrates stated, “all disease begins in the gut”. We now understand that impairment of the barrier...
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