Unique features of our technology.
Locsense contributes to enhancing discoveries in drug development, improve compound testing in the drug and food industry and toxicological research. We develop and design in-vitro sensing equipment that enables early phase drug discovery and supports animal free methods.
The Locsense Artemis is used to monitor barrier strength, crucial for drug testing, disease research, and understanding body defenses. Our devices integrate seamlessly with existing workflows and advanced in-vitro platforms like organ-on-chip and microfluidic chips.
Automated TEER / impedance spectroscopy measurements
Monitor the barrier function while cells are situated inside the incubator or on the laboratory bench
User-friendly and workflow compatible
The software is plug and play and the system is easy to operate for first time users
Time-saving
Save time by automating TEER / impedance spectroscopy measurements for several hours or days at the desired time intervals
Non-destructive, semi-continuous
The Artemis operates while cells are located inside the incubator, hood or on the desktop. Measurements are non-destructive and can be performed for days in a row and intervals of your choice.
Compatible with conventional transwell plates
Smart-lids are available for 12 and 24 wells transwell plates, including Nunc, Corning, VWR, Greiner.
Reduced risk of cross contamination
Each well is equipped with a set of electrodes, thereby reducing the risk of cross contamination. All parts in contact with cells are autoclavable
Solid product, responsive team
The Locsense Artemis delivers exactly what we need: continuous impedance measurements, a straightforward software interface, and hardware that’s easy to move between work stations. Support has been above and beyond, feedback is welcomed and often acted on quickly. Solid product, responsive team.
Quantifying skin barrier properties
The skin is important for keeping our bodies hydrated, guarding us from harmful substances and UV radiation, and protecting us from infectious agents. Tissue cultures can closely mimic the morphology of healthy human skin, but quantifying the skin’s barrier has ever been a difficult and work-intensive procedure.
We acquired the Artemis some years ago and this enabled us to measure the electrical impedance through our skin equivalent tissue cultures. We found that we’re not just measuring tissue volume or thickness, but were able correlate barrier protein expression levels to impedance values – truly quantifying the barrier properties of our cell cultures. In addition, using the Artemis over the course of the cell culture can help us monitoring the development of the tissue cultures. Furthermore, using the Artemis we are able to decide on the ideal experimental set-up during the culture, instead of knowing in hind-sight whether our experimental approach was right.
The Artemis is easy to set up and can measure the impedance of a full 24-well plate within minutes. With cell culture plastics sometimes scarce, it is reassuring that the Artemis can measure impedance in different brands of cell culture plastics, not limiting us to specific cell culture plastics. We enjoy working together with Locsense as they are very open to user feedback and willing to amend the Artemis and working to develop software packages that help the end user even further.
Boosting Barrier Integrity Research
“We have been working with the Artemis ST in combination with 24 wells plates during a rental period and were impressed by its performance.
Recently, we purchases one, allowing us to continue utilizing it in our experiments. The Artemis has been instrumental in generating reliable data on barrier integrity across various in vitro models, significantly enhancing the robustness of our experimental setups.
Moreover, the Artemis has enabled us to investigate time-dependent barrier effects, which we were previously unable to study in-depth. Its user-friendly interface and space-efficient design make it an excellent addition to our laboratory.
The Locsense team has consistently demonstrated professionalism and dedication, always putting in effort to meet our needs. Their support in experimental setup and data analysis has been very valuable. We look forward to continuing our collaboration with Locsense and incorporating the Artemis further in our research.”
Revolutionizing Laboratory Workflows
“The Artemis has become an essential piece of technology in a majority of the experimental and quality control workflows in our laboratory.
This system has enabled us to establish reliable, rapid and cost-effective methodologies to assess bioelectrical parameters of cells and tissues. This advancement has sped up our development of sophisticated human-like organ and tissue models. The Artemis is now a key tool for testing the quality of these models and assessing the safety of nanoparticles (such as air pollutants), as well as the safety and efficacy of new therapeutics (like extracellular vesicles) for repairing various organs.
Additionally, using the Artemis has significantly reduced the number of tests needed to evaluate the models and decreased the use of plasticware in the lab, contributing to the sustainability of our research. Lastly, the Locsense team has provided exceptional support with experimental setup and data analysis.”
Engage with us.
Reach out to us if you would like to receive more information about our products and collaboration opportunities. Whether you have questions, an exciting project in mind, or are simply curious about what we do, we are here for you.
